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In vivo effect of snake phospholipase A2 (crotoxin+cardiotoxin) on serum IL-1alpha, TNF-alpha and IL-1ra level in humans.

06/08/2001 /221 Comentarios/en /por

Immunol Lett. 2001 Jan 1;75(2):137-41. Costa LA, Fornari MC, Berardi VE, Miles HA, Diez RA . VRCTC-310-Onco (crotoxin, a secretory phospholipase A2+cardiotoxin) is under development as an anti-neoplastic agent. Pro-inflammatory cytokines TNF-alpha and interleukin 1 alpha (IL-1alpha) and anti-inflammatory cytokine IL-1 receptor antagonist (IL-1ra) were measured with commercial ELISA kits in sera corresponding to 23 […]

Neutrophil respiratory burst activity and pro- and anti-inflammatory cytokines in AAA surgery: conventional versus endoluminal treatment.

04/13/2001 /4.876 Comentarios/en /por

J Endovasc Ther. 2001 Apr;8(2):114-24 Parodi JC1, Ferreira LM, Fornari MC, Berardi VE, Diez RA. Abstract PURPOSE: To examine the inflammatory impact of endovascular and conventional surgery of abdominal aortic aneurysm (AAA) as assessed by the activation of neutrophils and serum levels of pro- and anti-inflammatory cytokines. METHODS: Twenty-four patients undergoing AAA exclusion were treated […]

Guillain-Barre syndrome following 2-chlorodeoxyadenosine treatment for Hairy Cell Leukemia.

11/08/2000 /757 Comentarios/en /por

Leuk Lymphoma. 2000 Nov;39(5-6):657-9. Sarmiento MA, Neme D, Fornari MC, Bengió RM. A 68-year-old man, with Hairy Cell Leukemia developed a Guillain-Barré syndrome (G-B), 32 days after a single course of 2-Chlorodeoxyadenosine (CDA) at 0,14 mg/k/d, for five days in a two-hour-i.v. infusion and following a febrile neutropenia episode. In order to clarify whether this […]

[In defense of aminophylline]

04/08/1999 /166 Comentarios/en /por

Medicina (B Aires). 1999;59(4):409-10.Comment on:Medicina (B Aires). 1999;59(1):107-8. Guereño MT, Fornari MC, Livio DL, Diez RA. PMID: 10752208 [PubMed – indexed for MEDLINE] Related Articles Effects of theophylline on lymphocyte phosphodiesterase activity. [Gen Pharmacol. 1998] The properties of aminophylline. [Emerg Nurse. 2007] Ultrastructure of the tracheal epithelium after administration of aminophylline. [Sb Lek. 2001] [Apoptosis […]

Pre- and post-treatment serum levels of cytokines IL-1beta, IL-6, and IL-1 receptor antagonist in celiac disease. Are they related to the associated osteopenia?

03/08/1998 /285 Comentarios/en /por

Am J Gastroenterol. 1998 Mar;93(3):413-8 Fornari MC, Pedreira S, Niveloni S, González D, Diez RA, Vázquez H, Mazure R, Sugai E, Smecuol E, Boerr L, Mauriño E, Bai JC. OBJECTIVE: Decreased bone mineral density is a common finding in untreated celiac disease patients. However, the precise pathophysiology of osteopenia remains incompletely understood. Pathological features of […]

Growth hormone inhibits normal B-cell differentiation and neutrophils’ chemotaxis in vitro.

08/08/1994 /6.252 Comentarios/en /por

Int J Immunopharmacol. 1994 Aug;16(8):667-73 Fornari MC, Scolnik MP, Palacios MF, Intebi AD, Diez RA. In acromegalic patients we have previously described a low ability of B-lymphocytes to differentiate into plasma cells under PWM stimulation, and a decreased chemotaxis of polymorphonuclear leukocytes (PMN) towards N-formylmethionylphenilalanine (FMP). In this study we examined the effect of exogenous […]

Decreased chemotaxis of neutrophils in acromegaly and hyperprolactinemia

05/08/1994 /611 Comentarios/en /por

Eur J Endocrinol. 1994 May;130(5):463-8. Fornari MC, Palacios MF, Diez RA, Intebi AD. Both growth hormone (GH) and prolactin (PRL) modulate immune responses in vitro. We studied chemotaxis under agarose of polymorphonuclear cells from patients with acromegaly or hyperprolactinemia. Polymorphonuclear cells were purified by dextran sedimentation and subjected to stimulation with N-formylmethionyl-phenylalanine. The results showed […]